Aging Neurodegeneration Methods Others
C. elegans SIR-2.1 Interacts with 14-3-3 Proteins to Activate DAF-16 and Extend Life Span
Cell,125,1165-1177,2006Abstract Full
text
Checkpoint Proteins Control Survival of the Postmitotic Cells in Caenorhabditis elegans
Science,312,1381-1385,2006Abstract Full
text
A Conserved MST-FOXO Signaling Pathway Mediates Oxidative-Stress Responses and Extends Life Span
Cell,125,987-1001,2006Abstract Full
text
Overexpression of a Drosophila Homolog of Apolipoprotein D Leads to Increased Stress Resistance and Extended Lifespan
Current Biology,16,674-679,2006Abstract Full
text
Germ-Cell Loss Extends C. elegans Life Span through Regulation of DAF-16 by kri-1 and Lipophilic-Hormone Signaling
Cell,124,1055-1068,2006Abstract Full
text
SMK-1, an Essential Regulator of DAF-16-Mediated Longevity
Cell,124,1039-1053,2006Abstract Full
text
Resveratrol Prolongs Lifespan and Retards the Onset of Age-Related Markers in a Short-Lived Vertebrate
Current Biology,16,296-300,2006Abstract Full
text
Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6
Cell,124,315-329,2006Abstract Full
text
Neuronal Expression of p53 Dominant-Negative Proteins in Adult Drosophila melanogaster Extends Life Span
Current Biology,15,2063-2068,2005Abstract Full
text
Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients
Science,310,1193-1196,2005Abstract Full
text
Sir2 Blocks Extreme Life-Span Extension
Cell,123,655-667,2005Abstract Full
text
A Role for SIR-2.1 Regulation of ER Stress Response Genes in Determining C. elegans Life Span
Developmental Cell,9,605-615,2005Abstract Full
text
Uncoupling of Longevity and Telomere Length in C. elegans
PLoS Genetics,1,e30,2005Abstract Full
text
Suppression of Aging in Mice by the Hormone Klotho
Science,309,1829-1833,2005Abstract Full
text
Differential patterns of apoptosis in response to aging in Drosophila
PNAS,102,12083-12088,2005Abstract Full
text
A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans
Nature Genetics,2005Abstract Full
text
Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging
Science,309,481-484,2005Abstract Full
text
A systematic RNAi screen for longevity genes in C. elegans
Genes & Development,19,1544-1555,2005Abstract Full
text
Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria
Science,308,1909-1911,2005Abstract Full
text
Calories Do Not Explain Extension of Life Span by Dietary Restriction in Drosophila
PLoS Biol,3,e223,2005Abstract Full
text
JNK Extends Life Span and Limits Growth by Antagonizing Cellular and Organism-Wide Responses to Insulin Signaling
Cell,121,115-125,2005Abstract Full
text
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
PNAS,102,3105-3110,2005Abstract Full
text
Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly
Cell Metabolism,1,145-152,2005Abstract Full
text
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
Nature,433,760-764,2005Abstract Full
text
Anticonvulsant Medications Extend Worm Life-Span
Science,307,258-262,2005Abstract Full
text
Insulin regulation of heart function in aging fruit flies
Nature Genetics,36,1275-1281,2004Abstract Full
text
Nutrient Availability Regulates SIRT1 Through a Forkhead-Dependent Pathway
Science,306,2105-2108,2004Abstract Full
text
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
Nature,430,686-689,2004Abstract Full
text
Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase
Science,305,390-392,2004Abstract Full
text
Long-Lived Drosophila with Overexpressed dFOXO in Adult Fat Body
Science,305,361,2004Abstract Full
text
Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl
PNAS,101,10290-10295,2004Abstract Full
text
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
Nature,429,562-566,2004Abstract Full
text Supplemental data
The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila
Nature Cell Biology,
6,540-546,2004Abstract Full text
Long lifespan in worms with long telomeric DNA
Nature Genetics,
36,607-611,2004Abstract Full text
Regulation of Lifespan in Drosophila by Modulation of Genes in the TOR Signaling Pathway
Current Biology,14,885-890,2004Abstract Full
text Supplemental data
Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster
PNAS,101,7663-7668,2004Abstract Full
text
Premature ageing in mice expressing defective mitochondrial DNA polymerase
Nature,429,417-423,2004Abstract Full
text
C. elegans SGK-1 Is the Critical Component in the Akt/PKB Kinase Complex to Control Stress Response and Life Span
Developmental Cell,6,577-588,2004Abstract Full
text
Comparing genomic expression patterns across species identifies shared transcriptional profile in aging
Nature Genetics,36,197-204,2004Abstract Full
text
Modulation of mammalian life span by the short isoform of p53
Genes & Development,18,306-319,2004Abstract Full
text
Calorie restriction extends yeast life span by lowering the level of NADH
Genes & Development,18,12-16,2004Abstract Full
text
Regulation of C. elegans Longevity by Specific Gustatory and Olfactory Neurons
Neuron,41,45-55,2004Abstract Full
text
Yeast Life-Span Extension by Calorie Restriction Is Independent of NAD Fluctuation
Science,302,2124-2126,2003Abstract Full
text
Influence of TOR kinase on lifespan in C. elegans
Nature,426,620,2003Abstract Full
text
Aging Specifically Impairs amnesiac-Dependent Memory in Drosophila
Neuron,40,1003-1011,2003Abstract Full
text
Notch-Mediated Restoration of Regenerative Potential to Aged Muscle
Science,302,1575-1577,2003Abstract Full
text
Tissue-Specific Activities of C. elegans DAF-16 in the Regulation of Lifespan
Cell,115,489-502,2003Abstract Full
text
JNK Signaling Confers Tolerance to Oxidative Stress and Extends
Lifespan in Drosophila
Developmental Cell, 5,811-816,2003Abstract Full
text
Healthy Animals with Extreme Longevity
Science,
302,611,2003Abstract Full text
An Age-Induced Switch to a Hyper-Recombinational State
Science, 301,1908-1911,2003Abstract Full text
Demography of Dietary Restriction and Death in Drosophila
Science, 301,1731-1733,2003Abstract Full
text
Small molecule activators of sirtuins extend Saccharomyces
cerevisiae lifespan
Nature, 425,191-196,2003Abstract Full
text
Autophagy Genes Are Essential for Dauer Development and Life-Span
Extension in C. elegans
Science, 301,1387-1391,2003Abstract Full text
Genes that act downstream of DAF-16 to influence the lifespan of
Caenorhabditis elegans
Nature, 424,277-283,2003Abstract Full
text
Long-Lived C. elegans daf-2 Mutants Are Resistant to Bacterial
Pathogens
Science, 300,1921,2003Abstract Full
text
Regulation of Aging and Age-Related Disease by DAF-16 and
Heat-Shock Factor
Science, 300,1142-1145,2003Abstract Full
text
Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin
Resistance
Science, 300,1140-1142,2003Abstract Full text
Aging Reduces Proliferative Capacities of Liver by Switching
Pathways of C/EBPa Growth Arrest
Cell, 113,495-506,2003Abstract Full
text
Nicotinamide and PNC1 govern lifespan extension by calorie
restriction in Saccharomyces cerevisiae
Nature,
423,181-185,2003Abstract Full text
DAF-16 Target Genes That Control C. elegans Life-Span and
Metabolism
Science, 300,644-647,2003Abstract Full
text
Asymmetric Inheritance of Oxidatively Damaged Proteins During
Cytokinesis
Science, 299,1751-1753,2003Abstract Full text
Identification of a DAF-16 Transcriptional Target Gene, scl-1,
that Regulates Longevity and Stress Resistance in Caenorhabditis
elegans
Current Biology, 13,427-431,2003Abstract Full
text
Telomere dysfunction and Atm deficiency compromises organ
homeostasis and accelerates ageing
Nature, 421,643-648,2003Abstract Full
text
IGF-1 receptor regulates lifespan and resistance to oxidative
stress in mice
Nature, 421,182-187,2003Abstract Full text
Senescence, aging, and malignant transformation mediated by p53 in
mice lacking the Brca1 full-length isoform
Genes & Development,
17,201-213,2003Abstract Full text
A systematic RNAi screen identifies a critical role for
mitochondria in C. elegans longevity
Nature Genetics,
33,40-48,2003Abstract Full text
Rates of Behavior and Aging Specified by Mitochondrial Function
During Development
Science, 298,2398-2401,2002Abstract Full text
Longevity regulation by Drosophila Rpd3 deacetylase and caloric
restriction
Science, 298,1745,2002Abstract Full text
Timing Requirements for Insulin/IGF-1 Signaling in C. elegans
Science, 298,830-834,2002Abstract Full
text
Stochastic and genetic factors influence tissue-specific decline
in ageing C. elegans
Nature, 419,808-814,2002Abstract Full text
Spatio-temporal analysis of gene expression during aging in
Drosophila melanogaster
Aging Cell, 1,47-56,2002Abstract Full text
Presynaptic regulation of neurotransmission in Drosophila by the G
protein-coupled receptor Methuselah
Neuron, 36,105-119,2002Abstract Full
text
A Mutation in the ATP2 Gene Abrogates the Age Asymmetry Between
Mother and Daughter Cells of the Yeast Saccharomyces cerevisiae
Genetics, 162,73-87,2002Abstract Full text
Transcriptional Profile of Aging in C. elegans
Current
Biology, 12,1566-1573,2002Abstract Full text
Genetic Analysis of Tissue Aging in Caenorhabditis elegans: A Role
for Heat-Shock Factor and Bacterial Proliferation
Genetics,
161,1101-1112,2002Abstract Full text
Calorie restriction extends Saccharomyces cerevisiae lifespan by
increasing respiration
Nature, 418,344-348,2002Abstract Full
text
Regulation of Hypoxic Death in C. elegans by the Insulin/IGF
Receptor Homolog DAF-2
Science, 296,2388-2391,2002Abstract Full
text
Premature Aging in Mice Deficient in DNA Repair and Transcription
Science, 296,1276-1279,2002Abstract Full
text
Genome-Wide Transcript Profiles in Aging and Calorically
Restricted Drosophila melanogaster
Current Biology,
9,712-723,2002Abstract Full text
Dietary restriction in long-lived dwarf flies
Science,
296,319,2002Abstract Full text
High-quality life extension by the enzyme peptide methionine
sulfoxide reductase
PNAS, 99,2748-2753,2002Abstract Full
text
Regulation of life-span by germ-line stem cells in Caenorhabditis
elegans
Science, 295,502-505,2002Abstract Full text
Life extension in Drosophila by feeding a drug
PNAS,
99,838-843,2002Abstract Full text
p53 mutant mice that display early ageing-associated
phenotypes
Nature, 415,45-53,2002Abstract Full
text
A hormonal signaling pathway influencing C. elegans metabolism,
reproductive development, and life span
Developmental Cell,
1,841-851,2001Abstract Full text
Mitochondrial Electron Transport Is a Key Determinant of Life Span
in Caenorhabditis elegans
Developmental Cell, 1,633-644,2001Abstract Full
text
Regulation of the Caenorhabditis elegans longevity protein DAF-16
by insulin/IGF-1 and germline signaling
Nature Genetics,
28,139-145,2001Abstract Full text
Lifespan extension and delayed immune and collagen aging in mutant
mice with defects in growth hormone production
PNAS,
98,6736-6741,2001Abstract Full text
Influences of aging and caloric restriction on the transcriptional
profile of skeletal muscle from rhesus monkeys
PNAS,
98,5093-5098,2001Abstract Full text
A mutant Drosophila insulin receptor homolog that extends life-
span and impairs neuroendocrine function
Science,
292,107-110,2001Abstract Full text
Extension of life-span by loss of CHICO, a Drosophila insulin
receptor substrate protein
Science, 292,104-106,2001Abstract Full
text
Regulation of longevity and stress resistance by Sch9 in yeast
Science, 292,288-290,2001Abstract Full text
The effects of aging on gene expression in the hypothalamus and
cortex of mice
PNAS, 98,1930-1934,2001Abstract Full
text
Increased dosage of a sir-2gene extends lifespan in Caenorhabditis
elegans
Nature, 410,227-230,2001Abstract Full text
Localized Igf-1 transgene expression sustains hypertrophy and
regeneration in senescent skeletal muscle
Nature Genetics,
27,195-200,2001Abstract Full text
Extended Life-Span Conferred by Cotransporter Gene Mutations in
Drosophila
Science, 290,2137-2140,2000Abstract Full text
Genome-wide study of aging and oxidative stress response in
Drosophila melanogaster
PNAS, 97,13726-13731,2000Abstract Full
text Supplement data 7400 EST changes with age and paraquat (Excel file
for download)
Survival for immunity: the price of immune system activation for
Bumblebee workers
Science, 290,1166-1168,2000Abstract Full
text
G [alpha] i and G [alpha] o are target proteins of reactive oxygen
species
Nature, 408,492-495,2000Abstract Full text
Regulation of C. elegans Life-Span by Insulinlike Signaling in the
Nervous System
Science, 290,147-150,2000Abstract Full
text
Requirement of NAD and SIR2 for Life-Span Extension by Calorie
Restriction in Saccharomyces cerevisiae
Science,
289,2126-2128,2000Abstract Full text
Extension of Life-Span with Superoxide Dismutase/Catalase
Mimetics
Science, 289,1567-1569,2000Abstract Full
text
Gene-expression profile of the ageing brain in mice
Nature
Genetics, 25,294-297,2000Abstract Full text
Natural selection: Evolution of lifespan in C.
elegans
Nature, 405,296-297,2000Abstract Full
text
Mitotic Misregulation and Human Aging
Science,
287,2486-2492,2000Abstract Full text
Transcriptional silencing and longevity protein Sir2 is an
NAD-dependent histone deacetylase
Nature, 403,795-800,2000Abstract Full
text
Food and metabolic signaling defects in a Caenorhabditis elegans
serotonin-synthesis mutant
Nature, 403,560-564,2000Abstract Full
text
A Delayed Wave of Death from Reproduction in
Drosophila
Science, 286,2521-2524,1999Abstract Full
text
Regulation of lifespan by sensory perception in Caenorhabditis
elegans
Nature, 402,804-809,1999Abstract Full text
The SIR2/3/4 complex and SIR2 alone promote longevity in
Saccharomyces cerevisiae by two different mechanisms
Genes &
Dev, 13,2570-2580,1999Abstract
Full text
Signals from the reproductive system regulate the lifespan of
C-elegans
Nature, 399,362-366,1999Abstract Full
text
A cytosolic catalase is needed to extend adult lifespan in C.
elegans daf-C and clk-1 mutants.
Nature, 399,162-166,1999Abstract Full
text
Elimination of Replication Block Protein Fob1 Extends the Life
Span of Yeast Mother Cells
Molecular Cell, 3,447-455,1999Abstract Full text
Aging-dependent large accumulation of point mutations in the human
mtDNA control region for replication.
Science, 286,774-779,1999Abstract Full text
Gene Expression Profile of Aging and Its Retardation by Caloric
Restriction
Science, 285,1390-1393,1999Abstract Full
text Additional tables
Positive correlation between mammalian life span and cellular
resistance to stress.
Free Radic Biol Med, 26,495-500,1999Abstract
Cell Nonautonomy of C. elegans daf-2 Function in the Regulation of
Diapause and Life Span
Cell, 95,199-210,1998Abstract Full
text
Dual modes of aging in Mediterranean fruit fly
females.
Science, 281,996-998,1998Abstract Full
text
Extension of Drosophila lifespan by overexpression of human SOD1
in motorneurons.
Nat Gen, 19,171-174,1998Abstract Full
text
Neurodegeneration Aging Methods Others
TOR-Mediated Cell-Cycle Activation Causes Neurodegeneration in a Drosophila Tauopathy Model
Current Biology,
16,230-241,2006Abstract Full text
Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila
PNAS,
102,3777-3781,2005Abstract Full text
Pharmacological Rescue of Synaptic Plasticity, Courtship Behavior, and Mushroom Body Defects in a Drosophila Model of Fragile X Syndrome
Neuron,
45,753-764,2005Abstract Full text
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
Nature Genetics,
36,585-595,2004Abstract Full text
Dissecting the pathological effects of human A§40 and A§42 in Drosophila: A potential model for Alzheimer's disease
PNAS,
101,6623-6628,2004Abstract Full text
Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease
PNAS,
101,3224-3229,2004Abstract Full text
Disruption of Axonal Transport by Loss of Huntingtin or Expression
of Pathogenic PolyQ Proteins in Drosophila
Neuron,
40,25-40,2003Abstract Full text
Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates
Neurodegeneration in Spinocerebellar Ataxia Type 1
Cell,
113,457-468,2003Abstract Full text
Genetic modulation of polyglutamine toxicity by protein
conjugation pathways in Drosophila
Human Molecular Genetics,
11,2895-2904,2002Abstract Full text
Suppression of polyglutamine toxicity by a Drosophila homolog of
myeloid leukemia factor 1
Human Molecular Genetics,
11,2657-2672,2002Abstract Full text
Motoneuron Death Triggered by a Specific Pathway Downstream of
Fas: Potentiation by ALS-Linked SOD1 Mutations
Neuron,
35,1067-1083,2002Abstract Full text
Androgen-Dependent Neurodegeneration by Polyglutamine-Expanded
Human Androgen Receptor in Drosophila
Neuron, 35,855-864,2002Abstract Full text
The IGF-1/Akt Pathway Is Neuroprotective in Huntington's Disease
and Involves Huntingtin Phosphorylation by Akt
Developmental
Cell, 2,831-837,2002Abstract Full text
Human Wild-Type Tau Interacts with wingless Pathway Components and
Produces Neurofibrillary Pathology in Drosophila
Neuron,
34,509-519,2002Abstract Full text
Chaperone Suppression of a-Synuclein Toxicity in a Drosophila
Model for Parkinson's Disease
Science, 295,865-868,2002Abstract Full
text
Histone deacetylase inhibitors arrest polyglutamine-dependent
neurodegeneration in Drosophila
Nature, 413,739-743,2001Abstract Full text
Tauopathy in Drosophila: neurodegeneration without neurofibrillary
tangles
Science, 293,711-714,2001Abstract Full
text
Oxidative Damage Linked to Neurodegeneration by Selective
alpha-Synuclein Nitration in Synucleinopathy Lesions
Science,
290,985-989,2000Abstract Full text
Identification of genes that modify ataxin-1-induced
neurodegeneration
Nature, 408,101-106,2000Abstract Full text
A-to-I Pre-mRNA Editing in Drosophila Is Primarily Involved in
Adult Nervous System Function and Integrity
Cell,
102,437-449,2000Abstract Full text
Delaying the onset of Huntington's in mice
Nature,
404,721-722,2000Abstract Full text
Reversal of Neuropathology and Motor Dysfunction in a Conditional
Model of Huntingtons Disease
Cell, 101,57-66,2000Abstract Full text
A Drosophila model of Parkinson's disease
Nature,
404,394-398,2000Abstract Full text
Genetic Suppression of Polyglutamine Toxicity in
Drosophila
Science, 287,1837-1840,2000Abstract Full
text
Dopaminergic Loss and Inclusion Body Formation in alpha-Synuclein
Mice: Implications for Neurodegenerative Disorders
Science,
287,1265-1269,2000Abstract Full text
Molecular Basis of a Yeast Prion Species Barrier
Cell,
100,277-288,2000Abstract Full text
Rnq1: An Epigenetic Modifier of Protein Function in
Yeast
Mol Cell, 5,163-172,2000Abstract Full text
A putative Drosophila homolog of the Huntington's disease
gene
Hum Mol Gen, 8,1807-1815,1999Abstract Full text
Suppression of polyglutamine-mediated neurodegeneration in
Drosophila by the molecular chaperone HSP70.
Nat Gen,
23,425-428,1999Abstract Full text
Methods Aging Neurodegeneration Others
Site-specific genomic targeting in Drosophila
PNAS,
102,12483-12488,2005Abstract Full text
An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster
PNAS,
101,12980-12985,2004Abstract Full text
A deletion-generator compound element allows deletion saturation
analysis for genomewide phenotypic annotation
PNAS,
99,9948-9953,2002Abstract Full text
Targeted mutagenesis by homologous recombination in D.
melanogaster
Genes & Development, 16,1568-1581,2002Abstract Full
text
RNAi Triggered by Symmetrically Transcribed Transgenes in
Drosophila melanogaster
Genetics, 160,637-648,2002Abstract Full text
Genetic Analysis of Digestive Physiology Using Fluorescent
Phospholipid Reporters
Science, 292,1385-1388,2002Abstract Full
text
P[Switch], a system for spatial and temporal control of gene
expression in Drosophila melanogaster
PNAS, 98,12602-12607,2001Abstract Full
text
A conditional tissue-specific transgene expression system using
inducible GAL4
PNAS, 98,12596-12601,2001Abstract Full text
"Fluorescent Timer": Protein That Changes Color with
Time
Science, 290,1585-1588,2000Abstract Full text
Gene Targeting by Homologous Recombination in
Drosophila
Science, 288,2013-2018,2000Abstract Full
text
Quantitative Analysis of Gene Function in the Drosophila
Embryo
Genetics, 154,273-284,2000Abstract Full
text
Mosaic Analysis with a Repressible Cell Marker for Studies of Gene
Function in Neuronal Morphogenesis
Neuron, 22,451-461,1999Abstract Full
text
Others Aging Neurodegeneration Methods
The Circadian Gene Per1 Plays an Important Role in Cell Growth and DNA Damage Control in Human Cancer Cells
Molecular Cell,22,375-382,2006Abstract Full text
Drosophila Immunity: A Large-Scale In Vivo RNAi Screen Identifies Five Serine Proteases Required for Toll Activation
Current Biology,16,808-813,2006Abstract Full text
Allocrine Modulation of Feeding Behavior by the Sex Peptide of Drosophila
Current Biology,16,692-696,2006Abstract Full text
Loss of Glial Lazarillo, a Homolog of Apolipoprotein D, Reduces Lifespan and Stress Resistance in Drosophila
Current Biology,16,680-686,2006Abstract Full text
Drosophila host defense after oral infection by an entomopathogenic Pseudomonas species
PNAS,102,11414-11419,2005Abstract Full text
Tumor Suppressor HIC1 Directly Regulates SIRT1 to Modulate p53-Dependent DNA-Damage Responses
Cell,123,437-448,2005Abstract Full text
A Direct Role for Dual Oxidase in Drosophila Gut Immunity
Science,310,847-850,2005Abstract Full text
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
Cell,123,335-346,2005Abstract Full text
Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis
Cell,122,221-233,2005Abstract Full text
An Epidermal Barrier Wound Repair Pathway in Drosophila Is Mediated by grainy head
Science,308,381-385,2005Abstract Full text
Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor
PNAS,102,1122-1126,2005Abstract Full text
An Antioxidant System Required for Host Protection against Gut Infection in Drosophila
Developmental Cell,8,125-132,2005Abstract Full text
Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria
Nature Immunology,5,1175-1180,2004Abstract Full text
Role and Regulation of Starvation-Induced Autophagy in the Drosophila Fat Body
Developmental Cell,7,167-178,2004Abstract Full text
Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K Pathway
Developmental Cell,7,179-192,2004Abstract Full text
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
Cell,118,229-241,2004Abstract Full text
Convergent evidence for impaired AKT1-GSK3 signaling in schizophrenia
Nature Genetics,36,131-137,2004Abstract Full text
Dual Activation of the Drosophila Toll Pathway by Two Pattern Recognition Receptors
Science,302,2126-2130,2003Abstract Full text
A Protein Interaction Map of Drosophila melanogaster
Science,302,1727-1736,2003Abstract Full text
A Genetic Screen in Drosophila for Metastatic
Behavior
Science,302,1227-1231,2003Abstract Full text
Essential Roles for Ecdysone Signaling During Drosophila
Mid-Embryonic Development
Science,301,1911-1914,2003Abstract Full text
A Nutrient Sensor Mechanism Controls Drosophila
Growth
Cell,114,739-749,2003Abstract Full text
The Drosophila Mst Ortholog, hippo, Restricts Growth and Cell
Proliferation and Promotes Apoptosis
Cell,114,457-467,2003Abstract Full
text
hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell
Proliferation and Promotes Apoptosis in Conjunction with salvador and
warts
Cell,114,445-456,2003Abstract Full text
BAD and glucokinase reside in a mitochondrial complex that
integrates glycolysis and apoptosis
Nature,424,952-956,2003Abstract Full
text
Caspase Activity and a Specific Cytochrome C Are Required for
Sperm Differentiation in Drosophila
Developmental
Cell,4,687-697,2003Abstract Full text
The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is
Required for Normal Fat Metabolism
Current
Biology,13,790-795,2003Abstract Full text
painless, a Drosophila Gene Essential for
Nociception
Cell,113,261-273,2003Abstract Full text
Control of Fat Storage by a Drosophila PAT Domain
Protein
Current Biology,13,603-606,2003Abstract Full
text
Activation of the innate immunity in Drosophila by endogenous
chromosomal DNA that escaped apoptotic degradation
Genes and
Development,16,2662-2671,2002Abstract
Full text
Gene expression during the life cycle of Drosophila
melanogaster
Science,297,2270-2275,2002Abstract Full text
Identification of genes involved in Drosophila melanogaster
geotaxis, a complex behavioral trait
Nature
Genetics,31,349-353,2002Abstract Full text
Stress response genes protect against lethal effects of sleep
deprivation in Drosophila
Nature,417,287-291,2002Abstract Full
text
Ablation of Insulin-Producing Neurons in Flies: Growth and
Diabetic Phenotypes
Science,296,1118-1120,2002Abstract Full
text
Requirement for a Peptidoglycan Recognition Protein (PGRP) in
Relish Activation and Antibacterial Immune Responses in
Drosophila
Science, 296,359-362,2002Abstract Full
text
Supplemental data Supplemental data
pictures
The Drosophila immune response against Gram-negative bacteria is
mediated by a peptidoglycan recognition protein
Nature,
416,640-644,2002Abstract Full text
Functional genomic analysis of phagocytosis and identification of
a Drosophila receptor for E. coli
Nature, 416,644-648,2002Abstract Full
text
Drosophila's insulin/PI3-kinase pathway coordinates cellular
metabolism with nutritional conditions
Developmental Cell,
2,239-249,2002Abstract Full text
Drosophila Toll is activated by Gram-positive bacteria through a
circulating peptidoglycan recognition protein
Nature,
414,756-759,2001Abstract Full text
Drosophila immune deficiency (IMD) is a death domain protein that
activates antibacterial defense and can promote
apoptosis
Developmental Cell, 1,503-514,2001Abstract Full text
Genome-wide analysis of the Drosophila immune response by using
oligonucleotide microarrays
PNAS, 98,12590-12595,2001Abstract Full text
Fray, a Drosophila Serine/Threonine Kinase Homologous to Mammalian
PASK, Is Required for Axonal Ensheathment
Neuron,
28,793-806,2000Abstract Full text
The amnesiac Gene Product Is Expressed in Two Neurons in the
Drosophila Brain that Are Critical for Memory
Cell,
103,805-813,2000Abstract Full text
Ciboulot Regulates Actin Assembly during Drosophila Brain
Metamorphosis
Cell, 102,797-808,2000Abstract Full
text
Potent Analgesic Effects of GDNF in Neuropathic Pain
States
Science, 290,124-127,2000Abstract Full text
The Drosophila takeout Gene Is a Novel Molecular Link between
Circadian Rhythms and Feeding Behavior
Cell, 101,647-656,2000Abstract Full
text
Drosophila Futsch/22C10 Is a MAP1B-like Protein Required for
Dendritic and Axonal Development
Neuron, 26,357-370,2000Abstract Full
text
Impaired Nociception and Pain Sensation in Mice Lacking the
Capsaicin Receptor
Science, 288,306-313,2000Abstract Full text
Drosophila p53 Binds a Damage Response Element at the reaper
Locus
Cell, 101,103-113,2000Abstract Full text
Drosophila p53 Is a Structural and Functional Homolog of the Tumor
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Cell, 101,91-101,2000Abstract Full text
Debcl, a Proapoptotic Bcl-2 Homologue, Is a Component of the
Drosophila melanogaster Cell Death Machinery
J Cell Biol,
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Candidate Taste Receptors in Drosophila
Science,
287,1830-1834,2000Abstract Full text
Correlates of Sleep and Waking in Drosophila
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Science, 287,1834-1837,2000Abstract Full
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Rest in Drosophila Is a Sleep-like State
Neuron,
25,129-138,2000Abstract Full text
A pdf Neuropeptide Gene Mutation and Ablation of PDF Neurons Each
Cause Severe Abnormalities of Behavioral Circadian Rhythms in
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Cell, 99,791-802,1999Abstract Full
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Science, 286,2179-2184,1999Abstract Full
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Fluoxetine-Resistant Mutants in C. elegans Define a Novel Family
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Molecular Cell, 4,143-152,1999Abstract Full
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The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell
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Cell,
98,453-463,1999Abstract Full text
Nitric oxide contributes to behavioral, cellular, and
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Cell,
98,105-114,1999Abstract Full text
Autonomous Control of Cell and Organ Size by CHICO, a Drosophila
Homolog of Vertebrate IRS14
Cell, 97,865-875,1999Abstract Full
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The Drosophila Gene hid Is a Direct Molecular Target of
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Cell, 95,331-341,1998Abstract Full text
Direct Sensing of Heat and Oxidation by Drosophila Heat Shock
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Molecular Cell, 2,101-108,1998Abstract Full
text